Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development: Correction
نویسندگان
چکیده
Correction There is an error in the Materials and methods section of our recent manuscript [1]. In our description of BrdU detection , the phrase "the embryos were treated with 2 N NaOH for 1 hr" should read as "the embryos were treated with 2 M HCI for 1 hr". We regret the mistake. The original article can be viewed at [ Verbatim copying and redistribution of this article are permitted in any medium for any purpose, provided this notice is preserved along with the article's original URL. Publish with BioMed Central and every scientist can read your work free of charge "BioMedcentral will be the most significant development for disseminating the results of biomedical research in our lifetime."
منابع مشابه
Mechanisms of spinal cord injury regeneration in zebrafish: a systematic review
Objective(s):To determine the molecular and cellular mechanisms of spinal cord regeneration in zebrafish. Materials and Methods: Medical databases of PubMed and Scopus were searched with following key words: Zebrafish; spinal cord injuries; regeneration; recovery of function. The map of mechanisms was performed using Xmind software. Results: Wnt/ß-catenin signaling, L1.1, L1.2, Major vault prot...
متن کاملFGF-dependent Notch signaling maintains the spinal cord stem zone.
Generation of the spinal cord relies on proliferation of undifferentiated cells located in a caudal stem zone. Although fibroblast growth factor (FGF) signaling is required to maintain this cell group, we do not know how it controls cell behavior in this context. Here we characterize an overlooked expression domain of the Notch ligand, Delta1, in the stem zone and demonstrate that this constitu...
متن کاملRegulation of neuronal specification in the zebrafish spinal cord by Delta function.
The vertebrate spinal cord consists of a large number of different cell types in close proximity to one another. The identities of these cells appear to be specified largely by information acquired from their local environments. We report here that local cell-cell interactions, mediated by zebrafish homologues of the Drosophila melanogaster neurogenic gene, Delta, regulate specification of dive...
متن کاملThe interplay between DSL proteins and ubiquitin ligases in Notch signaling.
Lateral inhibition is a pattern refining process that generates single neural precursors from a field of equipotent cells and is mediated via Notch signaling. Of the two Notch ligands Delta and Serrate, only the former was thought to participate in this process. We now show that macrochaete lateral inhibition involves both Delta and Serrate. In this context, Serrate interacts with Neuralized, a...
متن کاملDelta-Notch signaling regulates oligodendrocyte specification.
Oligodendrocytes, the myelinating cell type of the central nervous system, arise from a ventral population of precursors that also produces motoneurons. Although the mechanisms that specify motoneuron development are well described, the mechanisms that generate oligodendrocytes from the same precursor population are largely unknown. By analysing mutant zebrafish embryos, we found that Delta-Not...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- BMC Developmental Biology
دوره 2 شماره
صفحات -
تاریخ انتشار 2002